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A Case Study of Effect of Binder Type on Dry Granulation

OBJECTIVE
The purpose of the present investigation was to compare the impact of roller compaction processing parameters and resulting tableting properties of roller compacted granules of Avicel ® DG (ADG) [Spray Dried-Co-processed Microcrystalline Cellulose], physical mixture of Avicel ® 101 (75%) and Anhydrous Di-calcium Phosphate) (25%)] (PADCP), and Co-Povidone [Kollidon ® VA-64 Fine] (KVA64).

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